There is a lot of research going on into reversing the damage done to the body by the seven known causes of aging. On this page we list the most promising developments and their targets, per cause of ageing.

Cell loss, tissue atrophy

Cancerous cells (DNA mutations)

Mitochondrial mutations

Death-resistant cells

Extracellular matrix stiffening

Extracellular aggregates (junk outside cells)

• Clearance of TTR amyloid: addresses the clogging of blood vessels by misfolded protein clumps, which is the suspected cause of death of many people that die of ‘old age’.

Intracellular aggregates (junk inside cells)

References